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Investigating the Impact of 60 days Head-Down-Tilt (HDT) Bed Rest on the Metabolic Physiology of Young, Healthy Males

HDT bed rest is used extensively in the context of space physiology to simulate microgravity exposure but it is also considered as a model of muscle disuse and physical inactivity. Physical inactivity induces insulin resistance and is an independent risk factor for multiple chronic diseases. This research is determining whether HDT bed rest alters the circulating concentrations of novel biomarkers of insulin resistance and if these changes impact whole-body insulin sensitivity. In addition to this, the project is investigating whether reactive jump training (<4 minutes/day), a countermeasure designed to preserve skeletal muscle mass, can alleviate the metabolic disturbance that occurs with prolonged inactivity.

PhD Student

Email Address

k.ward@research.ait.ie

Latest Publication

Ward, K., Mulder, E., Frings-Meuthen, P., O’Gorman, D.J. & Cooper, D. (2020). Fetuin-A as a Potential Biomarker of Metabolic Variability Following 60 Days of Bed Rest. Frontiers in Physiology. 11:573581.

Kiera Ward

Kiera completed her undergraduate degree in AIT, where she studied Sports Science with Exercise Physiology. Kiera’s research is funded by the European Space Agency’s PRODEX programme and Enterprise Ireland. Supervisors: Dr Niamh Ní Chéilleachair, Dr Diane Cooper and Dr Donal O’Gorman (DCU).